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The Revolutionary Skin Repair Cream: Protect the Skin Ecosystem and Support Better Healing

Reading time : 6 min

Cream for healing

The skin’s microbiome plays an important role in healing skin when it is weakened. Science first showed the importance of cleaning pathogenic microorganisms from damaged skin – and has now also shown how the skin’s microbiome participates in the healing process.

 

Following the latest scientific discoveries, Laboratoire Bioderma has transformed the formula of its iconic scar healing cream to create Cicabio CrEAM+. Developed from the study of the skin’s ecosystem and natural biology, it’s the first ecobiological repairing soothing cream to optimise the skin’s healing process while preserving its ecosystem. 

healing cream

Recognising the skin microbiome's role in healing damaged skin

 

 

A cesarean section, a superficial scratch or cut, a peel or maybe a tattoo, our skin can be weakened in any number of ways, voluntary or involuntary. Recent scientific studies have demonstrated that the skin microbiome is key to the healing process. The microbiome helps to prevent infection and inflammation and supports skin reconstruction. 

Skin microbiome diversity and skin healing

 

The more healthy and diverse the skin’s microbiome, the more significantly it contributes to helping the epidermis heal well. Acting on the skin’s surface, the microbiome helps to reduce colonisation and infection by pathogenic bacteria, calm inflammation, and regrow tissue. It’s therefore essential to support the microbiome so that it can play its part during healing.

 

Bioderma Cicabiot Crème+ for healing process

A Bioderma ecobiological innovation

 

Cicabio CrEAM+

 

First ecobiological repairing soothing cream*

it considers skin as an ecosystem that interacts with its environment and has its own natural mechanisms to care for itself. 

 

RESTORE MICROBIOME & OPTIMISE HEALING PROCESS

helps to strengthen these mechanisms using biomimetic ingredients that repair skin by restoring microbiome diversity, optimising the healing process, and soothing itching and sensations of discomfort. 

 

*BIODERMA - developed from the study of the skin’s ecosystem and natural biology.

 

DISCOVER THE PRODUCT

As a result of this new knowledge about the skin microbiome, Bioderma has reinvented its iconic healing cream. Cicabio CrèmE is now Cicabio CrEAM+ and it has a new approach, a new formula and a new texture.

 

Cicabio CrEAM+  is the new healing reference for weakened skin. The ultra-repairing soothing cream to heal weakened skin

 

Do you want to know more about CICABIO products composition?

  • Decode our products composition

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Repairing the skin

 

There are four overlapping stages to the skin’s healing process: stopping blood flow, calming inflammation, reconstructing tissue and reaching maturity. Each stage relies on a healthy skin microbiome and the skin being able to carry out its healing mechanisms. Cicabio CrEAM+ has been formulated to nourish the microbiome and optimise the healing process. 

 

 

Restore microbiome diversity

 

The microorganisms that live on skin feed on elements such as the sebum we produce and have adapted to skin’s slightly acidic environment. Cicabio CrEAM+ formula respects and supports this ecosystem, helping to recreate favorable conditions where the skin’s microbiota can flourish.

 

Cicabio CrEAM+ contains biomimetic lipids that include squalene, which is found in sebum, and it has a pH the same as skin’s.

Recognising the ingredients as part of its own composition, the skin absorbs them into its natural mechanisms, smoothing the overall healing process. 

 

 

Biomimetic ingredients to optimize the healing process

 

Those mechanisms require a humid environment to rebuild skin tissues and structures. Bioderma’s new and patented Optimal repair complex** has three biomimetic ingredients with complementary actions.

 

  1. Polyglutamic acid retains 3,000 times its weight in water, keeping the skin’s surface moisturised as it heals.

  2. Hyaluronic acid penetrates deeper into the epidermis, hydrating skin cells as they repair.

  3. Xylose is a restructuring agent that boosts collagen production, making skin strong. A clinical study has measured an 88% increase in skin repair after seven days 1, thanks to the Optimal Repair Complex. 

 

**Patent application filed in France. 

1In vitro study on reconstructed skin model, epidermal closure at D7 after topical application of Optimal repair complex vs. untreated

 

 

Soothing itching and discomfort sensations

 

Skin that is healing can feel uncomfortable and often gets itchy. While this is normal, rubbing or scratching can interrupt healing, and only serves to prolong the process. Bioderma’s Antalgicine™ biomimetic technology is inspired by a molecule naturally present in the body whose role is to soothe unpleasant sensations.

 

Antalgicine™ therefore soothes these sensations of discomfort and itching. Healing has fewer interruptions, which leads to faster healing and less scarring in the end. 

cream texture of Cicabio Crème+

AN ADAPTED SENSORIAL TEXTURE 

 

In an easy-to-spread and pleasant, non-sticky and non-greasy texture, Cicabio CrEAM+ forms a breathable and protective film on skin. Acting almost like a shielding bandage, it aids the skin’s healing mechanisms as soon as you apply it. 

 

RESULTS**

 

  • 100% texture facilitates scar massage

 

  • 96% texture is pleasant and easy to apply

 

  • 94% texture has a protective effect that lets skin breathe 

 

 

** Clinical study with Cicabio Cream+ on remodeling scars (C-section, episiotomy, adhesions) on 34 patients, % of satisfaction at D7 and at D14.

 

Full-body tolerance and effectiveness, for all weakened skin

 

 

Skin can be weakened for any number of reasons, including superficial cuts and scratches, cosmetic procedures, surgery, nappy rash and getting a tattoo. For use anywhere on the face, body, scalp and external intimate areas, Cicabio CrEAM+ is perfectly adapted to the needs of the whole family. 

 

 

Clinically proven to repair skin and minimise marks

 

 

Tested under dermatological, paediatric, gynaecological and ophthalmological supervision, Cicabio Crème+ has been clinically proven to restore the microbiome and help skin repair itself in the right conditions.  

 

  • restores the skin’s microbiome1 from 3 hours after application
     
  • 88% drop in itching and sensations of discomfort2 
     
  • 46% red marks lessened by 46% 2
     
  • 32% drop in thickness2

  • 45% increase in skin’s suppleness *2

 

 

1 Clinical study after disinfection, restoration of Shannon index (diversity and relative abundance of bacteria) 3 hours post-application of Cicabio Crème+ vs untreated disinfected zone, on 20 subjects

2 Clinical study of Cicabio Crème+ on remodeling scars (C-section, eipisiotomy, adhesions) on 34 subjects, scoring at D14 vs D0

*Evalutation of the pliability of the skin

 

 

Cicabio CrEAM+ SPF50+

 

Optimal healing for weakened skin, without hyperpigmentation 

 

 

If skin that is healing is exposed to UV rays, permanent scarring and dark marks can form. Weakened skin therefore needs to be protected from UV exposure. For this kind of situation, Cicabio CrEAM+ also exists with SPF50+ broad-spectrum UV protection. The new triple action complex prevents marks from appearing on skin as it heals. 

 

 

Triple action complex to avoid hyperpigmentation while weakened skin heals

 

 

Cicabio CrEAM+ SPF50+ provides the same optimal healing and soothing while respecting the skin’s ecosystem, and augments this with a triple action complex that prevents marks from forming. 

 

 

  • Protects from UV rays

 

Both UVA and UVB filters are present in the formula, to block the rays and provide broad-spectrum protection from sun exposure. 

 

 

  • Fights against oxidative stress and helps skin repair

 

A lipo-peptide contributes to reducing oxidative stress. It also helps to heal skin. 

 

 

  • Inhibits the production of melanin

 

To further protect against dark marks forming, glabridine helps to stop melanin from being synthesized. With less melanin, there is less chance for hyperpigmentation to occur. 

 

 

Discover the product

 

 

Clinically proven for its effectiveness and skin tolerance

 

 

Cicabio CrEAM+ SPF50+ has been tested under dermatological, paediatric and ophthalmological supervision. It can be used by the whole family anywhere on your face, body and scalp. 

 

 

  • 16,7% drop in hyperpigmentation after 3 days1A 
     
  • 69% immediate drop in burning sensations 1B

 

  • 27% immediate drop in redness 1C
     
  • 100% of subjects say they’re satisfied by Cicabio Cream+ SPF50+’s effectiveness at protecting 1D

  

 

 

1 Clinical study with Cicabio Cream+ SPF50+ on post-laser on face for 14 days – 31 subjects with a tendency to hyperpigmentation,

(A) Scoring by dermatologist, D3 vs. D0 post-laser

(B) Auto-scoring, immediately after application on D0 post-laser

(C) Scoring by dermatologist, immediately after application on D0 post-laser

(D) Auto-satisfaction, from D3.